Empowering Enterprise AI with AMD Instinct MI350P PCIe Cards

As artificial intelligence becomes central to business innovation, many organizations face challenges with their existing IT infrastructure. While cloud-based AI offers scalability, it often raises concerns around data privacy and unpredictable expenses. On-premises upgrades, especially those involving large GPU-accelerator platforms, can demand significant investments in power and cooling redesigns. AMD Instinct MI350P PCIe cards introduce a new approach: delivering high-performance AI acceleration that integrates seamlessly into your current data center environment.

Seamless Integration with Existing Data Center Infrastructure

The AMD Instinct MI350P PCIe cards are engineered for straightforward deployment in standard air-cooled servers, making them an ideal solution for enterprises preparing for the next wave of agentic AI. These dual-slot, drop-in cards are designed to fit directly into your existing racks, leveraging your current power and cooling infrastructure. This PCIe form factor is particularly advantageous for organizations seeking enhanced AI compute capabilities beyond CPUs, without the need for dedicated GPU platforms or extensive data center modifications.

Supporting up to eight accelerator cards in air-cooled systems, AMD Instinct MI350P PCIe cards are well-suited for a wide range of AI workloads, from small and medium models to large-scale inference and retrieval-augmented generation (RAG) pipelines. This flexibility allows enterprises to scale their AI initiatives efficiently, regardless of where they are on their AI adoption journey.

Maximizing AI Performance and Return on Investment

AMD Instinct MI350P PCIe cards are purpose-built to deliver industry-leading AI performance while optimizing cost efficiency. Key features include:

  • Native support for lower-precision MXFP6 and MXFP4, enabling high-throughput AI inference.
  • Advanced sparsity support for mainstream 8- and 16-bit precisions, accelerating a broad range of AI models.
  • Estimated 2,299 TeraFLOPS (TFLOPS) and up to 4,600 peak TFLOPS at MXFP4—setting a new standard for enterprise PCIe cards.
  • 144 GB of high bandwidth memory 3e (HBM3E) with speeds up to 4 TB/s, ensuring rapid data access for demanding workloads.
  • An open ecosystem with accessible development stack options, reducing deployment complexity and operational costs.

These capabilities empower organizations to move from AI evaluation to production outcomes, scaling both performance and return on investment without the need for costly infrastructure overhauls.

Open, Flexible Enterprise AI Software Ecosystem

AMD Instinct MI350P PCIe cards are built on open standards, supporting cross-platform interoperability and customer choice. The AMD enterprise AI stack integrates seamlessly with a broad ecosystem of AI software and tools, including Kubernetes GPU Operator for lifecycle management, cloud-native AMD Inference Microservices, and native support for leading AI frameworks such as PyTorch.

The open-source AMD enterprise AI reference stack is available to partners at no licensing cost, promoting code transparency and helping to reduce ongoing expenses. Combined with AMD Instinct MI350P PCIe cards and partner solutions, this stack enables rapid, on-premises AI deployment without recurring per-token charges.

Precision and Efficiency for Enterprise AI Workloads

AMD Instinct MI350P PCIe cards support a comprehensive range of precision levels essential for enterprise AI models. Lower-precision formats like MXFP6 and MXFP4 deliver maximum throughput and efficient model execution, while higher-precision types such as INT8 and BF16 benefit from advanced sparsity support for optimized performance.

With native support for FP8, MXFP8, and MXFP4, these cards are uniquely capable of handling modern AI workloads within standard, air-cooled data centers. This design not only maximizes GPU throughput but also reduces memory usage, helping to lower power and cooling requirements.

Accelerate AI Adoption Without Infrastructure Overhaul

AMD Instinct MI350P PCIe cards enable enterprises to transition from bare-metal infrastructure to production-ready AI systems with minimal disruption. Workloads can be migrated without extensive code rewrites, and the cards integrate smoothly with existing AI pipelines, supporting scalable growth as business needs evolve.